ea0063p228 | Pituitary and Neuroendocrinology 1 | ECE2019
Taieb Ach
, Ines Barka
, Asma Ben Abdelkrim
, Yosra Hasni
, Amel Maaroufi
, Maha Kacem
, Molka Chaieb
, Koussay Ach
Introduction: Pituitary insufficiency is a late-onset sequel of cranial irradiation for nasopharyngeal tumors. In a Cancer Survivor Study, 43% of patients treated for nasopharyngeal tumors had one or more endocrinopathies. We aim to characterize the pituitary-related outcomes following cranial radiotherapy for nasopharyngeal tumors over a period of 5 years.Material and methods: The effects of cranial irradiation on hypothalamic-pituitary function were st...